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Factor D
Factor D (, ''C3 proactivator convertase'', ''properdin factor D esterase'', ''factor D (complement)'', ''complement factor D'', ''CFD'', ''adipsin'') a protein which in humans is encoded by the ''CFD'' gene.〔(【引用サイトリンク】 url =http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1675 )〕 Factor D is involved in the alternative complement pathway of the complement system where it cleaves factor B. == Function ==
The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.〔 Factor D is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Factor D」の詳細全文を読む
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